Chemistry Professors Go Three-for-Three with ACS Grants – Hobart and William Smith Colleges \
The HWS Update

Chemistry Professors Go Three-for-Three with ACS Grants

Any chemistry department would be proud to have three research proposals simultaneously pending, but to have all three proposals funded in the same funding cycle is truly an amazing accomplishment

(Nov. 17, 2003) GENEVA, N.Y.—Hobart and William Smith chemistry professors Christine de Denus, Erin Pelkey and Carol Parish have recently learned that each of their American Chemical Society-Petroleum Research Fund proposals have been funded. All three faculty members run very active research programs with students throughout the year, and these grants will help them to continue to do so.

Pelkey and de Denus received grants of $35,000 to be used over two years for summer salary for the principal investigator, student stipends, supplies, equipment and travel. Parish’s grant, the maximum amount of which is $50,000 for three years, funds research that includes participation by undergraduate students. A $500 annual departmental allocation is also included in this grant.

The project de Denus will be undertaking focuses on the development of materials that may be candidates for molecular wire technology. Molecular wires currently are being investigated as a replacement for silicon chip technology.

Pelkey will work on developing new methods for synthesizing a class of molecules collectively known as the Aristolactam alkaloids. A subset of these compounds has been shown to possess promising anti-cancer activity.

Parish’s project investigates the fundamental molecular relationships between small molecule drugs and their protein or nucleic acid targets. Her work has specific applications to the molecular structures, energies and behavior of anti-HIV and anti-cancer drugs.

HWS Professors background:
Professor Christine de DenusAn assistant professor of chemistry, de Denus received her Ph.D. from the University of Manitoba in 1997 and her B.S. from the University of Winnipeg in 1993. Prior to joining the Hobart and William Smith faculty in 1999, she completed a prestigious two-year Natural Sciences and Engineering Research Council of Canada post-doctoral fellowship in the department of chemistry at The Pennsylvania State University. In addition to her teaching and research, she is also a reviewer for the American Chemical Society, the Journal of Inorganic and Organometallic Polymers, Macromolecules and the International Journal of Science and Technology.

Professor Erin PelkeyPelkey joined the Colleges faculty in the summer of 2001. He earned his B.A. from Carleton College, his Ph.D. from Dartmouth, and was an NIH postdoctoral fellow at Stanford University. His research interests lie in the field of organic chemistry. Pelkey is a member of Sigma Xi, the American Chemical Society, the International Society of Heterocyclic Chemistry and the Council of Undergraduate Research. For the past several years he has written a review chapter on thiophene chemistry in the annual series “Progress in Heterocyclic Chemistry,” published by Elsevier.

Professor Carol ParishParish, associate professor of chemistry at Hobart and William Smith since 1997, holds a B.S. and M.S. from Indiana University-Purdue University and a Ph.D. from Purdue University. She also has pursued post-doctoral training at Columbia University. Parish has conducted extensive research ranging from drug design to pain inhibition that has been published in several publications, including the Journal of the American Chemical Society and the Journal of Physical Chemistry. In addition to her teaching and research, Parish has served on the board of the ACS Women Chemists Committee. She is currently on sabbatical leave as a visiting research professor at Cornell University.

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