Macaluso Wins RISE Fellowship – Hobart and William Smith Colleges \
The HWS Update

Macaluso Wins RISE Fellowship

Hobart junior selected for competitive German program

(April 18, 2005) GENEVA, N.Y.—Hobart junior Max Macaluso has always wanted to study abroad, but he didn't want to leave campus and interrupt his research of anti-cancer drugs. Now his study of chemistry has given him the opportunity to experience another culture and another country through the support of the competitive German Academic Exchange Service’s Research Internships in Science and Engineering (RISE) fellowship.

The fellowship connects highly-qualified American or Canadian undergraduates, like Macaluso, with German Ph.D. students, providing competent research assistants for the Ph.D. candidates. The undergraduate students get a glimpse of advanced research work while gaining desirable practical experience in their field. In addition to lab work, the undergraduates also learn German culture and language.

Macaluso’s work this summer will be both computational and experimental. His time in the research laboratory of Peter Schreiner at Justus-Liebig University in Giessen, Germany will be spent designing new molecules on a computer and then synthesizing them in an organic synthesis lab.

“I will be working on the synthesis of novel hydrocarbon bowls and sheets,” says Macaluso. “These structures have very diverse applications, from electronics to drug delivery. This will be my first experience in an organic synthesis lab, and my first time in Germany, as well. I'm very excited about this opportunity.”

Macaluso’s work at Hobart and William Smith Colleges has revolved around cancer research. He spent the summers of 2003 and 2004 studying the electronic structure of anti-cancer enediyne warhead drugs and the role that tautomerization plays in the cyclization. He presented the results of his study at the 2003 and 2004 MERCURY supercomputer conference at Hamilton College, at the 2004 national American Chemical society meeting in Philadelphia and in numerous regional and local forums. In 2004, Macaluso was the first author on a publication describing his results in the Journal of Organic Chemistry, along with Carol Parish, associate professor of chemistry at the Colleges, Roald Hoffmann, 1981 Nobel Laureate and professor of chemistry at Cornell University and Larry Scott, professor of chemistry at Boston College.

The son of Nicholas and Grace Macaluso of Canandaigua, N.Y., Macaluso is a biochemistry major with an environmental studies minor. He is the recipient of a 2003 Merck/American Association for the Advancement of Science Summer Research Fellowship, as well as a 2004 Patchett Summer Research Fellowship. A Hobart Dean’s Scholar, Macaluso was recently awarded a grant from the American Cancer Association for Cancer Research and has received the Phi Phi Delta Scholarship, the CRC First-Year Chemistry Achievement Award and the PolyEd Award for Achievement in Organic Chemistry.

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A high-resolution photo of Macaluso is available at http://campus.hws.edu/new/releases/hiRes/macaluso_max_hres.jpg.